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LUBBOCK, Texas -- Texas had no answer for Kliff Kingsbury, and now there's no chance for a national title.
Kingsbury threw for 473 yards and six touchdowns as Texas Tech upset the Longhorns 42-38 on Saturday.
"We tried everything," Texas coach Mack Brown said. "And he whipped everything we tried."
Kingsbury also lifted Texas Tech into the South race.
The Red Raiders visit Oklahoma on Saturday with the winner advancing to the title game.
"We just have to do the same like we did (Saturday)" to beat Oklahoma, Tech coach Mike Leach said. "We need to get a lot of first downs, make good punts and complete passes."
A loss to Oklahoma last month all but eliminated the Longhorns from the conference race, but they had an outside chance of reaching the BCS' national title game.
"They all hurt any time you lose," said quarterback Chris Simms, who threw for 345 yards and four touchdowns. "To be so close and have things fall the way they did, it's tough."
Tech went ahead 42-38 on a 25-yard pass from Kingsbury to Taurean Henderson with 5:41 left.
On the next possession, Simms was intercepted by Ryan Aycock.
Texas' defense came in ranked fifth nationally, allowing 261 yards per game. But Texas Tech had 306 by halftime and finished with 606.
With his big day, Kingsbury, who completed 38 of 60 passes, moved up to fourth in Division I history with 11,831 yards.
COLORADO 41, IOWA ST. 27: Bobby Purify ran for 174 yards and a touchdown as the host Buffaloes clinched their second straight North title.
Colorado won despite losing Chris Brown during the third quarter. Brown, the nation's leading rusher, left with a bruised sternum after running for 127 yards and a touchdown on 25 carries.
Seneca Wallace's 6-yard touchdown run cut the Cyclones' deficit to 34-27. But Purify responded by carrying all six times on a six-play, 80-yard scoring drive. His 50-yard run down the left sideline set up his 5-yard score that sealed it.
KANSAS ST. 49, NEBRASKA 13: Quarterback Ell Roberson ran for 228 yards and three touchdowns as the host Wildcats earned their most lopsided victory against Nebraska.
Roberson's 91-yard first-quarter touchdown was the second-longest run against Nebraska, topped only by a 99-yarder by Kansas' Gale Sayers in 1963. It was the longest Kansas State run since Gerald Hackney's 96-yarder against the Jayhawks in 1948.
Roberson's rushing output, on 29 carries, was the best by a Kansas State quarterback, breaking Michael Bishop's record of 196 set against Missouri in 1997. It was the second-best rushing day ever for the Wildcats, behind Mike Lawrence's 252 yards against Iowa State in 1996.
Darren Sproles added 155 rushing yards and three touchdowns, including a 70-yarder late.
Roberson's long run put the Wildcats ahead 14-0. He also had a 1-yard keeper for a touchdown on the opening drive and a 25-yarder during the fourth that made it 35-13.
Nebraska had 97 yards on the ground (38 in the first half), and Jammal Lord was sacked six times and held to 21 yards on 47 carries.
OKLAHOMA 49, BAYLOR 9: Quentin Griffin ran for 152 yards and three touchdowns and had a 35-yard touchdown catch as the visiting Sooners rebounded from their first loss.
It was Griffin's sixth consecutive 100-yard rushing game. He has 885 yards in the six games and 1,243 this season.
Oklahoma earns a spot in the league championship if it wins its final two games against Texas Tech and Oklahoma State.
The Sooners extended a 21-3 halftime lead with touchdowns on their first three possessions of the second half. All three took 1:31 or less.
MISSOURI 33, TEXAS A&M 27 (2OT): Brad Smith's 1-yard touchdown run gave the visiting Tigers a victory after blowing a two-touchdown halftime lead.
The Aggies had the ball first in the second overtime. But Michael Harden intercepted a pass by Dustin Long, who replaced Regie McNeal after he left with an undisclosed injury.
In the first overtime, Missouri's Michael Matheny and A&M's Todd Pegram kicked 40-yard field goals.
Long helped A&M rally from 17-3 down at halftime. And after Missouri took a 24-17 lead on Justin Gage's 32-yard touchdown catch, Long led the drive that tied it. Joe Weber capped it with a 1-yard run, his second touchdown of the game, with 15 seconds left.
OKLAHOMA ST. 55, KANSAS 20: Josh Fields threw a school-record six touchdowns for the visiting Cowboys.
Rarely pressured while facing a defense ranked 111th in Division I-A, Fields erased the record, held by three players, with five touchdowns during the first half.
The first three went to Rashaun Woods, the conference's leading receiver who had 171 yards and three scores on seven receptions.
Fields went 17-of-26 for 354 yards, raising his season total to 2,235 yards and making him the second Cowboy to pass for more than 2,000 yards in a season.