NEW YORK - Derek Jeter returned to a familiar sight: the Anaheim Angels beating up on his Yankees.
Scott Spiezio hit two homers, including a grand slam, to send Mike Mussina to his first loss of the season in the Angels' 10-3 win Tuesday night.
Garret Anderson added a two-run homer and David Eckstein went 4-for-5 for the Angels, who beat the Yankees in the first round of last year's playoffs. John Lackey allowed two runs in six innings for Anaheim, which hadn't played at Yankee Stadium since rallying to win Game 2 of the playoffs, starting the comeback that culminated in the team's first World Series title.
Jeter went 1-for-4 in his first game off the disabled list after missing six weeks with a dislocated left shoulder. Jeter, who hurt himself on a headfirst slide on opening night in Toronto, didn't need to make any plays to test his shoulder in his return.
New York went 25-11 during Jeter's absence, winning two of three in Anaheim. The Yankees have lost three of their past four overall.
Spiezio snapped a 25 at-bat hitless streak in the fourth inning against Mussina with a drive off the facing of the upper deck in rightfield. He hit the slam in the ninth off Juan Acevedo for his sixth career multihomer game.
Mussina, bidding to become the first AL pitcher since Dave Stewart in 1988 to win his first eight starts, didn't look comfortable from the start.
He gave up hits to four of the first 10 batters but held the Angels scoreless until Anderson's two-run homer with two outs in the third. It was the first homer allowed by Mussina since his first start of the season, when he allowed one to Toronto's Carlos Delgado.
The Angels added an unearned run in the fifth when second baseman Alfonso Soriano couldn't handle Anderson's sinking liner, allowing Adam Kennedy to score from second on the error.
Mussina, who had won nine straight regular-season starts dating to last season, allowed four runs, three earned, and six hits in five innings.
He failed in his attempt to win his first eight starts of the season. Pedro Martinez was the last pitcher to do it in 1997 for Montreal and no Yankees pitcher had done it since Eddie Lopat in 1951.
Lackey has struggled since becoming the first rookie to win Game 7 of the World Series in 93 years. He went into the game with a 7.38 ERA and was winless in his past five starts.
He had allowed 11 first-inning runs in his first eight starts and looked like he would add to that total when he began the game with five straight balls.
With Soriano on second after a steal, Lackey retired the next 12, including Jeter on a foul pop in his first at-bat.
Hideki Matsui opened the fifth with a clean single to center and scored on Robin Ventura's one-out homer down the rightfield line. That snapped a 14-inning scoreless streak at home for New York.
The Angels added two runs in the seventh against Sterling Hitchcock.
