HOUSTON - Freshman Kevin Kolb threw for two touchdowns and rushed for two Saturday night to lead Houston to a 48-14 victory over crosstown rival Rice, making coach Art Briles a winner in his debut.
Kolb, named the starter ahead of sophomore Blade Bassler shortly before the annual Bayou Bucket game, finished 17-of-22 for 246 yards and no interceptions in the opener for both teams.
Brandon Middleton caught four passes for 122 yards and two scores.
Vincent Marshall had eight receptions for 95 yards and threw a crushing block that sprung Middleton for his second TD, which came on a short pass that Middleton took 55 yards down the right sideline to make it 41-7 midway into the third quarter.
Kolb set the tone in the first quarter when, with Houston ahead 3-0, he faced a second-and-31 after a double penalty on the Houston offense.
He responded with a 47-yarder to Middleton, who beat linebacker Jeff Vanover near the goal line and took it in.
After Houston took a 17-0 lead with the first of two 1-yard touchdown dives by Kolb, Rice showed signs of life despite losing halfback Clint Hatfield with a sprained left ankle.
Greg Henderson capped a quick 74-yard drive with a 22-yard keeper around the right end for a touchdown.
Henderson added a 1-yard TD run in the fourth quarter. He led Rice with 73 yards rushing.
The margin of victory was Houston's largest in the series since 1989, when both were in the Southwest Conference and Andre Ware led the Cougars to a 64-0 victory moments before claiming the Heisman Trophy.
MEMPHIS 40, TENNESSEE TECH 10: DeAngelo Williams scored three touchdowns, caught four passes for 135 yards and rushed for 61 more to lead the host Tigers.
Williams caught touchdowns of 80 and 28 yards in the third quarter and had a 1-yard scoring run in the first half.
Maurice Avery had touchdown runs of 33 and 3 yards for the Tigers.
Division I-AA Tennessee Tech, winless in 15 tries against I-A teams, trailed 31-3 after Williams' third-quarter scores.
It was a record-breaking night for Memphis quarterback Danny Wimprine, who completed 15-of-21 for 266 yards to establish school marks for career yards (4,415) and completions (352).
Steve Matthews (1992-93) held the mark for completions with 341; Danny Sparkman (1983-85) held the mark for yards with 4,311.
Avery's 33-yard touchdown came on a reverse in the first quarter for a 10-0 Tiger lead.
The only Tennessee Tech score in the first half came on a 39-yard field goal by Josh Foster as time expired, cutting the Tiger lead to 17-3.
The offensive highlight for the Golden Eagles came in the third quarter when Craft hit Derek Lee for a 65-yard touchdown.