INDIANAPOLIS - When Reggie Wayne heard Colts fans chanting his name, some teammates insisted he was in the wrong place.
Peyton Manning had him right where he wanted.
Wayne produced the best game of his career, catching 10 passes for 141 yards and two touchdowns, nearly all in the second half, as he carried Indianapolis to a 23-13 victory over the Jaguars.
"It's not Reggie Miller today; it's Reggie Wayne," the third-year receiver said. "So I can enjoy it for one day."
The chants of "Reg-gie! Reg-gie!" typically have been reserved in Indianapolis for Miller, the Pacers' all-time leading scorer. Sunday, for the first time, the chant reverberated inside the RCA Dome, and for good reason.
Wayne did it all as the Colts improved to 3-0 for the first time since 1996 and second since 1978.
He went across the middle, won battles on deep routes and made impressive runs after the catch and terrific adjustments. He finished with career highs in receptions and yards and matched a career high in touchdowns.
He played the way the Colts expected him to when they made him their first-round pick out of Miami in 2001, and everybody responded.
"They rolled the coverage to Marvin (Harrison) and Peyton did a good job with his reads," coach Tony Dungy said. "Reggie came through. These are the kinds of games we expect him to have. If they do that, he's got to make them pay."
The Colts cashed in with what is becoming their trademark: a stifling defense and an offense that keeps finding lesser-known weapons and plays just well enough to win.
For the Jaguars, it was too much to defend.
They couldn't cover Wayne for most of the second half, then dropped their fifth straight dating to last season.
"It's real frustrating to stop Harrison and (Edgerrin) James and to have that happen," cornerback Jason Craft said. "But you have to know they have other guys who can beat you, too."
Harrison finished with four catches for 31 yards. James ran 27 times for 76 yards, and Manning was 21-of-33 for 216 yards, mostly when Wayne burned Craft repeatedly in the second half.
Wayne caught one pass for 11 yards in the first half, but with the Colts trailing 3-0 Manning started throwing his way.
On the third play of the second half, Manning found Wayne for 9 yards. Six plays later, Wayne broke free in the corner of the end zone and Manning connected with a 28-yard touchdown.